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Therapeutic S100A8/A9 blockade inhibits myocardial and systemic inflammation and mitigates sepsis-induced myocardial dysfunction

Even more impressive, about 86% of participants had a weight reduction of 5% or more from their baseline body weight by the end of the study

doi: 10.1210/en.2007-0442 69 TuzcuAYalakiSArikanSGokalpDBahcecMTuzcuSet al

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Eligibility also depends on a full health evaluation to ensure the treatment is safe and appropriate for each persons medical history

76,77 The mechanisms through which this occurs are not fully elucidated, although basic science and clinical studies have shown that GLP-1 agonists have immunomodulatory effects by reducing proinflammatory cytokines and altering immune cell populations